Enantioselective hydrogenation in aqueous-media
Martin Rahmel held a lecture on the advantages of enantioselective hydrogenation at the Green Solvents Conference in Dresden (October 20-22).
To illustrate a recent advance for the application of aqueous catalysis, he presented how DexLeChem found a way for the successful asymmetric hydrogenation of ketones with commercially available BINAP-type ruthenium complexes. Working in aqueous media enables organic-solvent free reactions, that result the same activity and selectivity as obtained for the identical reaction in organic solvents. Catalysis in water not only provides a much “greener” reaction but also offers the advantage of catalyst re-using.